Abstract
Family-focused therapy (FFT) has been shown to be effective in stabilization of mood symptoms in youth at risk for bipolar disorder. Less is known about the underlying brain changes that occur in response to treatment, particularly as it relates to family problem solving. In this study, we compared pre- to posttreatment fMRI activation patterns between FFT and a comparison therapy from a randomized controlled trial. We also examined the relative role of the components of FFT [psychoeducation vs. family skills training (FST)] on changes in the brain after treatment.
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