Abstract
The specific dermatoses of pregnancy represent a heterogeneous group of inflammatory skin diseases and include pemphigoid gestationis (PG), polymorphic eruption of pregnancy (PEP), intrahepatic cholestasis of pregnancy (ICP), and atopic eruption of pregnancy (AEP). Pruritus is the primary symptom and should be taken seriously in a pregnant woman. Clinical characteristics, in particular the morphology and distribution of lesions as well as the timing of their appearance relative to the stage of gestation, are crucial for diagnosis. The diagnoses of PG and ICP are confirmed via specific immunofluorescence and laboratory findings, respectively. PEP and AEP are distressing only to the mother because of associated pruritus, whereas PG may be associated with prematurity and small-for-gestational age neonates and ICP poses an increased risk for fetal distress, prematurity, and stillbirth. Corticosteroids and antihistamines control PG, PEP and AEP, whereas ICP is best treated with ursodeoxycholic acid.
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