Abstract
In the title compound, C13H15F2NO, the piperidine ring adopts a chair conformation. The dihedral angle between the least-squares plane of the piperidine ring and the benzene ring is 48.75 (7)°. In the crystal structure, the molecules are connected via C—H⋯O hydrogen bonds, forming a zigzag chain along the b axis.
Highlights
In the title compound, C13H15F2NO, the piperidine ring adopts a chair conformation
The molecules are connected via C—H O hydrogen bonds, forming a zigzag chain along the b axis
NMDA receptor antagonist properties of piperidine-2-carboxylic acid derivatives have been reported (El Hadri et al, 1995). Due to their biological importance of piperidine derivatives, we have present the crystal structure of the title compound (I)
Summary
School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia, bSchool of Chemical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia, and cX-ray Crystallography Unit, School of Physics, Universiti Hydrogen-bond geometry (Å, ). R factor = 0.045; wR factor = 0.136; data-to-parameter ratio = 22.7. Symmetry code: (i) x; y þ 12; z þ 12. In the title compound, C13H15F2NO, the piperidine ring adopts a chair conformation. The dihedral angle between the leastsquares plane of the piperidine ring and the benzene ring is 48.75 (7) . In the crystal structure, the molecules are connected via C—H O hydrogen bonds, forming a zigzag chain along the b axis.
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