Abstract
Background: The gold standard treatment for nodulocystic acne vulgaris, isotretinoin, is contraindicated in patients with a soy allergy as its capsule contains hydrogenated soybean oil. This has raised concern for its use in patients with peanut and cashew allergies due to the potential for cross-reactivity. Cashew allergy has been reported to confer a greater risk of cross-reactivity to soy, resulting in rare allergic reactions to isotretinoin. This case series sought to further evaluate the safety of isotretinoin use in eleven patients with a history of peanut or cashew allergy.
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