268: Perinatal and neonatal outcomes of triplet gestations based on method of conception

Abstract

METHOD OF CONCEPTION JEFFREY SPENCER, CHARLES INGARDIA, JAMES EGAN, CHRISTOPHER NOLD, KATE SMITH, WINSTON CAMPBELL, University of Connecticut Health Center, Farmington, Connecticut, Hartford Hospital, Hartford, Connecticut OBJECTIVE: To evaluate differences in perinatal and neonatal outcomes in triplet gestations based on method of conception: assisted reproductive technology (ART) vs. spontaneous (SPONT). STUDY DESIGN: We analyzed all triplet sets ( 20 weeks) delivering at our institutions from 1/95-4/07 (n 137). Data was obtained via perinatal and neonatal databases, chart review, and placental pathology. ART included in vitro fertilization, intrauterine insemination, and ovulation induction. We collected demographic data, gestational age of delivery (AOG), birthweight, APGARS, length of NICU stays, need for intubation (VENT), need for surfactant (SURF), rates of bronchopulmonary dysplasia (BPD), respiratory distress syndrome (RDS), intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), and culture proven sepsis (SEPSIS). We excluded cases of known fetal reduction and sets with incomplete data. Data was analyzed via t test and Chi square. RESULTS: We had 130 triplet sets available for analysis. 111/130 (85.4%) sets were conceived via ART. There was no significant difference in AOG (31.6 wks for ART, 33.1 wks for SPONT, p NS). Please see table for individual triplet results. CONCLUSION: At our institutions, there were no overall differences in outcomes of triplet gestations based on method of conception.