26738 Assessing the cosmetic changes in the facial skin using noninvasive RCM and OCT in vivo skin imaging instrumentation after use of a topical retinoid product in subjects with moderate to severe photodamage

Abstract

There are limited studies assessing cosmetic skin changes using reflectance confocal microscopy (RCM) and optical coherence tomography (OCT). To explore the cosmetic effects of a topical cosmetic retinoid (RET05) a study was conducted using RCM and OCT. A twelve-week, open-label study was conducted to assess the effects of RET05 on subjects with facial photodamage. Study endpoints included investigator grading, standardized (VISIA-CR) and 3D Photography (Antera3D), independent RCM (VivaScope1500) and OCT (VivoSight) image analysis, validated FACE-Q scales, and subject questionnaires.