Abstract
Tumor repopulation has a significant impact on low-dose-rate brachytherapy (1). As for its effect in external-beam radiotherapy (EBRT), there is an ongoing debate on the onset time of tumor repopulation for prostate cancer. Is it short around 4 weeks as assumed by Wang et al (1) or as long as over 200 days and can be ignored as argued by Fowler et al (2)? The purpose of this study is to estimate the tumor repopulation rate and its onset time for prostate cancer by analyzing published EBRT data.
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