Abstract
The heterogeneity of cancers limits the reproducibility of anticancer target-biomarker associations in diverse cohorts or sample groups. Here, we carried out consensus analyses of cancer omics data to find improved consistency (reproducibility) of prognostic power of biomarkers and anticancer potential of targets. Overall, ∼74% of prognostic RNA expression in patient samples were exclusively found in a single lineage, and most of them did not pass the cross-validation within the given lineage. Prognostic RNA expression (i.e., biomarker) showing subtype consensus within the lineage, also tend to exhibit high consensus in other lineages.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
