Abstract

Recent advances in biologic therapy have revolutionized the treatment of psoriasis. Risankizumab, a humanized monoclonal antibody targeting interleukin 23A, is the newest Food and Drug Administration (FDA)-approved biologic agent for the treatment of moderate-to-severe plaque psoriasis. Due to its potential immunomodulating effect, considerations for serious infections such as hepatitis B (HBV) and hepatitis C (HCV) are important when initiating biologic therapy; in particular, the serious complications of HBV and HCV reactivation.

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