Abstract

Breast cancer constitutes the second most common cause of BMs with a higher prevalence in patients with triple-negative and HER2-positive mBC. T-DXd, an antibody-drug conjugate targeting HER2, has shown promising efficacy in patients with HER2-overexpressing mBC and treated asymptomatic BMs. We aimed to analyze the efficacy of T-DXd in patients with BMs and mBC according to HER2 status in patients from DAISY trial.

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