Abstract
Introduction: Postoperative seroma formation is one of the most common and serious complications after breast cancer surgery. It frequently appears after simple or radical mastectomies. Data from our recently published pilot study on immunological processes in seroma formation, showed a specific immune response of CD3+/CD4+ T helper (Th) cells. A significant increase of Th2 and Th17 was observed in both, seroma fluid and peripheral blood of the same patients while no increase was found in healthy controls.
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