Abstract

Background: Caveolin-1 (CAV1) is a master regulator of cell signaling and membrane transport. CAV1 has been implicated in breast cancer oncogenesis and metastasis and may be a potential prognosticator, especially for non-distant recurrences. Several CAV1 SNPs have been linked to other cancers, however, the prognostic impact of CAV1 SNPs in breast cancer remains unclear. Here, we investigated CAV1 haplotypes association with clinical outcomes in breast cancer.

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