255 Annual medication review by a clinical pharmacist in an adult cystic fibrosis care center

Abstract

Objectives The complexity of cystic fibrosis (CF) drug regimens is a major challenge for patients and CF specialists. A multidisciplinary approach is thus essential and a clinical pharmacist can help optimize medication. 2011's CF UK Trust suggests that patients should be seen annually by a pharmacist. The aim of this project was to implement a pharmacy consultation during the annual review, and to analyze the pharmaceutical interventions. Methods A one-hour interview with a clinical pharmacist and CF patients was included during their annual review. Pharmacists reviewed medication with patients using a form assessing the drug list, administration and storage items. A feedback was then given to CF physicians. The following parameters were recorded: number and types of a. patient s questions, b. pharmacist's interventions to patient or c. to physician. Results From December 2013 to December 2014, 2 pharmacists conducted 19 interviews. Mean age of the 19 patients (8 male, 11 female) was 32 (±10) years (range: 19–49). Medication lists contained a mean of 15.5 (±6.5) drugs, of which 76% were chronic and 24% were ‘as needed’. Per interview, patients had 2.2 (±1.7) questions, pharmacists addressed 1.5 (±1.1) interventions to patients and 1.6 (±1.3) to physicians. These concerned adverse events (17%), drug interactions (13%), drug stability and storage (11%), and dose timing (10%). Conclusion Pharmacy consultation permitted to address several issues of drug safety and use with CF patients, and to share relevant information with the CF team in order to optimize treatment. The satisfaction of the CF participants remains to be evaluated.