254 Risk Factors for Prevalence Symptoms of Eczema in Polish Children According to Ecap Study

Abstract

The aim of this paper was to identify familial and environmental factors that are associated with increased AD risk in children.Material and methods: Epidemiology of Allergic Diseases in Poland study (ECAP) was randomized, multicentre, cohort study, based on personal national identification number, performed in 2006-2008. The completed questionnaires were collected from 9231 children. According to ISAAC protocol 6-7 year-old (n=4510) and 13-14 year-old children (n=4721) participated in ECAP study. The questionnaire based on ISAAC was used. Statistical significance was defined as p< 0.005.Results: Of the total 9231 children AD symptoms were observed in 3908 (42.3%) (45.8%;n=2066 and 39.0%;n=1842). There was an increase risk of eczema among tobacco smokers (35.0%) vs no smokers (32.4%) (OR=1.11, 95%CI: 1.02-1.21). The eczema prevalence in household with visible moulds was 44.7% and without moulds 35.5% (OR=1.47; 95%CI: 1.38-1.57). Multivariate logistic regression analysis showed that more frequent AD symptoms correlated with older mother (OR=1.20; 95%CI: 0.96-1.49). Strong associations were found between the number of cars and lorries went near patient's home and more eczema presence (respectively: OR=1.64, 95%CI: 1.22-1.75; OR=1.16, 95%CI: 1.06-1.26). High socioeconomic status and high prevalence of AD were strong correlated (OR=1.37; 95%CI: 1.26-1.48). There was a significant association between spending more than 1 hour per day watching TV and less prevalence of eczema (OR=0.83; 95%CI: 0.74-0.92).Conclusions: Significant risk factors for incident AD were: tobacco smoking, household with visible moulds, older mother, traffic-related air pollution and high socioeconomic status. Long TV watching were associated with decreased risk of AD.