Abstract
Backg round: Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality worldwide A well - characterized IL8 gene single - nucleotide polymorphism (SNP) at position −251 A/T is the only one known to influence its expression and was associated with several diseases. Aim: To investigate the possible correlation of the − 251 A/T polymorphism of IL - 8 gene with susceptibility to Acute Myocardial infarction and its correlation with Plasma IL - 8 levels in two case control populations , the Saudi and Egyptian populations. Methods : 20 AMI patients and 20 asymptomatic controls from Saudi population in addition to 20 AMI patients and 20 asymptomatic controls from Egyptian population were included in the current study. The IL - 8 plasma level was assayed using the human IL - 8 Quantikine ELISA Kit . The IL - 8
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