Abstract
IntroductionBenign paroxysmal positional vertigo is the most common cause of dizziness in the general population. It is a condition with potential impact of reduced levels of vitamin D on its recurrent attacks.ObjectivesThe aim of this study was to measure the serum levels of 25-hydroxyvitamin D3 (25-OH D3) in patients with benign paroxysmal positional vertigo and determine whether there is a difference in the serum levels of vitamin D3 between patients with and without recurrence, as well as between the different clinical forms of benign paroxysmal positional vertigo.MethodsThe study included 40 patients who came to the regular medical examination, diagnosed with posterior canal-benign paroxysmal positional vertigo based on the positive Dix-Hallpike's test. All patients underwent Epley manoeuvre after the diagnosis. Patients were classified according to current guidelines for levels of vitamin D3 in the serum in three groups: the deficiency, insufficiency and adequate level.ResultsThe average serum level of 25-OH D3 among respondents was 20.78 ng/mL, indicating a lack or insufficiency of the aforementioned 25-OH D3. According to the levels of 25-OH D3, most patients suffer from deficiency (47.5%). 7 (17.5%) respondents had adequate blood level of 25-OH D3, and 14 (35%) respondents suffer from insufficiency. A significant difference was not found in the serum level of 25-OH D3 between patients with and without benign paroxysmal positional vertigo recurrence. There was a significant difference in the serum levels of 25-OH D3 in comparison to the clinical form of the disease. Lower 25-OH D3 values were found in patients with canalithiasis compared to those with cupulolithiasis.ConclusionsThere were no significant differences in the vitamin D3 serum level in patients with and without recurrence. The study showed a low level of serum vitamin D3 in most patients, indicating the need for supplemental therapy.
Highlights
Benign paroxysmal positional vertigo is the most common cause of dizziness in the general population
While 25-OH D3 form of the vitamin D represents most of the active vitamin D form in plasma/serum, 25OH D2 form is present in significant quantities during the replacement therapy with vitamin D2.23---25 The main objectives of this study were to determine whether there are differences in the serum 25-OH D3 level among respondents suffering from Benign paroxysmal positional vertigo (BPPV) regarding age, sex, clinical form, and single episode/recurrence of the disease
There was no significant difference between gender groups regarding age, free calcium and vitamin D3 levels (Table 2)
Summary
Benign paroxysmal positional vertigo is the most common cause of dizziness in the general population. It is a condition with potential impact of reduced levels of vitamin D on its recurrent attacks. Patients were classified according to current guidelines for levels of vitamin D3 in the serum in three groups: the deficiency, insufficiency and adequate level. According to the levels of 25-OH D3, most patients suffer from deficiency (47.5%). Benign paroxysmal positional vertigo (BPPV) is the most common cause of dizziness in the general population with a lifetime prevalence of about 10%.1. The disease occurs spontaneously, clinically manifests in short seizures, intensive vertigos that are caused by a certain position of the head and are often accompanied by vegetative symptoms. Head injuries lead to the occurrence of BPPV in about 17% of cases,[5] and viral
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
