Abstract
Background: Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by multiple hamartomas in different organs. Classic triad, found exclusively in 29% of patients, involves facial angiofibromas, mental retardation, and epilepsy. Dermatologic manifestations appear in 90% of patients, including facial angiofibromas, fibrous cephalic plaques, hypomelanotic macules, Koebner tumours, and shagreen patches.
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