2425: Contrast-enhanced ultrasound prior to percutaneous focal liver lesions biopsy

Abstract

Objectives: To evaluate the clinical utility of contrast-enhanced ultrasound in percutaneous focal liver lesion biopsy. Methods: One hundred eighty-six patients with focal liver lesions were randomly divided into two groups, contrast-enhanced ultrasound group (CEUS group) and ultrasound group (US group). CEUS group underwent SonoVue contrast-enhanced ultrasound (CEUS) prior to biopsy and US group did not undergo CEUS prior to biopsy. Conventional ultrasound (US) was used in all patients to guide the biopsy procedures. The diagnostic accuracy of the initial biopsy was defined as the percentage of the total number of lesions that were correctly diagnosed at the initial biopsy. The difference in diagnostic accuracy between the two groups was analyzed to evaluate the value of CEUS prior to biopsy. Results: The diagnostic accuracy of the initial biopsy was significantly higher in CEUS group than US group (p < 0.05). The diagnostic accuracy of the initial biopsy for malignant lesions ≤ 2.0 cm in size was also significantly higher in CEUS group than US group (p < 0.05). No major complications occurred in our study except one case of pneumothorax in US group. Conclusions: CEUS prior to percutaneous focal liver lesion biopsy improved the diagnostic accuracy of this procedure and reduced the number of puncture attempts.