241 The association between sodium intake and atopic dermatitis in a US population-based cohort

Abstract

Diet may be an important environmental factor driving the onset and persistence of atopic dermatitis. Recent evidence showing that most of the body’s exchangeable sodium is stored in the skin and that high sodium environments trigger and perpetuate local immune dysregulation support the hypothesis that excessive dietary sodium intake could be associated with atopic dermatitis. We aimed to investigate this hypothesis using data from 13,183 children and adults in the 1999-2000, 2001-2002, and 2003-2004 cycles of the National Health and Nutrition Examination Survey, which included validated dietary intake questionnaires and questions about participants’ history of dermatitis, eczema, or rash.