Abstract
Coeliac disease is a gastrointestinal disorder caused by intolerance to cereals due to an immunological mechanism. It is the most common cause of poor absorption in the developed countries. It has heterogeneous clinical and pathological features. Neurological and psychiatric disorders have been reported, such as epilepsy, occipital calcifications epilepsy (Goby’s syndrome), axonal polyneuropathy, cerebella syndromes, brain atrophy and dementia, schizophrenia, autism and depression. The pathogenic mechanism of these disorders is not completely clear although biochemical factors such as low serum concentrations of vitamin E and vitamin B6 may be a cause. The most frequent symptom of epilepsy in celiac patients is sudden, brief loss of consciousness. We present a 16-year-old girl with celiac disease who suffered from loss of consciousness. CT scan was normal. Neurophysiological studies showed normal EEG, PESS, PEAT and ENG. However, PEV showed a marked delay in P100 wave latency, with greater involvement of the left eye. An exhaustive review of the literature showed only a few papers discussing the neurophysiological changes seen in celiac disease.
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