Abstract
Metastasis is a critical factor for the high mortality in Non-small-cell lung carcinoma (NSCLC), but the mechanism is still not completely understood. DAB2IP, as a Ras GTPase-activating protein and novel scaffold protein, is involved in the progression of various cancers. Previously, it was reported that DAB2IP methylation status in circulating DNA could predict response to erlotinib in EGFR-mutated NSCLC patients. However, the role of DAB2IP in NSCLC has rarely been investigated.
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