Abstract
Beckmann rearrangement of N-[3-(1-hydroxyimino)ethyl-2,2-dimethylcyclobutyl]acetylanthranilic acid, and its 5-bromo and 4-chloro derivatives gives the corresponding N-(3-acetylamino-2,2-dimethylcyclobutyl)acetylanthranilic acids. Treatment of these acylanthranilic acids with formamide gives 2-(3-acetylamino-2,2-dimethylcyclobutyl)methyl-4(3H)-quinazoline and its 6-bromo and 7-chloro derivatives. Authors: F. M. Avotin'sh, M. V. Petrova, N. N. Tonkikh, and A. Strakov. English Translation in Chemistry of Heterocyclic Compounds , 2000, 36 (11), pp 1326-1328 http://link.springer.com/article/10.1023/A%3A1017579719809
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