Abstract

Abstract Background People with HIV (PWH) are at increased risk for COVID-19 complications and thus can significantly benefit from COVID-19 vaccination. PWH are also more likely to belong to racial/ethnic minority groups that have been underrepresented among vaccinated individuals. The objective of this analysis was to identify Health Belief Model (e.g., perceived susceptibility to and severity of COVID-19, perceived barriers, and benefits of COVID-19 vaccination) and Social Ecological Model (i.e., intrapersonal, interpersonal, and community/institutional-level) factors associated with vaccine uptake among PWH. Methods The cross-sectional survey was administered by telephone in English, Spanish or Haitian Creole from January–March 2022 to a sample of 299 adult PWH receiving medical case management services through the Miami-Dade County Ryan White Program (MDCRWP). Participants who received a primary vaccine series were classified as fully vaccinated, and those that received only 1 dose of a 2-dose vaccine series or no doses were classified as not fully vaccinated. Multivariable logistic regression was used to estimate adjusted odds ratios (aORs) of full vaccination with 95% confidence intervals (CIs). The final adjusted model included all sociodemographic characteristics selected a priori, as well as covariates with a p-value < 0.2 in bivariate analyses. Analyses were weighted to be representative of the race/ethnicity and sex distribution of clients in the MDCRWP. Results The weighted percentages for full vaccination was 83.8% for the entire group, and 88.9% among Hispanics, 72.0% among African Americans, and 67.5% among Haitians. Being fully vaccinated was associated with Hispanic compared with African American race/ethnicity (aOR 5.44; 95% CI 1.50-19.77), not endorsing any misconceptions about COVID-19 vaccines (aOR 8.26; 95% CI 1.38-49.64), reporting encouragement to get vaccinated from their sources of information (aOR 20.82; 95% CI 5.84-74.14), and perception that ≥ 50% of social network was vaccinated (aOR 3.35; 95% CI 1.04-10.71) (Table 1). Conclusion Results highlight the importance of promoting accurate information from sources deemed trustworthy, and social networks in COVID-19 vaccine uptake among PWH. Disclosures All Authors: No reported disclosures

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