2375: The role of contrast-enhanced ultrasound in pancreatic diseases characterization

Abstract

Objectives: To observe the enhancement patterns of pancreatic diseases and evaluate the role of contrast-enhanced ultrasound (CEUS) in pancreatic diseases characterization compared with conventional ultrasound, contrast-enhanced CT (CECT) and biospy.Methods: Seventy-two patients with pancreatic diseases underwent CEUS using SonoVue, including 54 malignant and 18 benign cases. The time of the beginning of enhancement, peak enhancement, the beginning of wash-out and the transit time (from the beginning of enhancement to wash-out) of the diseased area and normal pancreatic tissue were analyzed for each case.Results: The beginning of enhancement of malignant pancreatic diseases was significantly slower than normal pancreatic tissue and the beginning of wash-out time was significantly faster than normal pancreatic tissue. The most common enhancement pattern of malignant diseases was peripheral enhancement with irregular nonenhanced area inside, while the benign diseases appeared homogeneous enhancement. The diagnostic accuracy of CEUS, CECT and biopsy in pancreatic diseases characterization was 87.5%, 81.8% and 92.7%, respectively, which were all significantly different from that of conventional ultrasound (56.9%). But there was no significant difference between CEUS and CECT.Conclusions: CEUS could improve the diagnostic ability in pancreatic diseases characterization. The diagnostic accuracy of CEUS is similar to CECT. Objectives: To observe the enhancement patterns of pancreatic diseases and evaluate the role of contrast-enhanced ultrasound (CEUS) in pancreatic diseases characterization compared with conventional ultrasound, contrast-enhanced CT (CECT) and biospy. Methods: Seventy-two patients with pancreatic diseases underwent CEUS using SonoVue, including 54 malignant and 18 benign cases. The time of the beginning of enhancement, peak enhancement, the beginning of wash-out and the transit time (from the beginning of enhancement to wash-out) of the diseased area and normal pancreatic tissue were analyzed for each case. Results: The beginning of enhancement of malignant pancreatic diseases was significantly slower than normal pancreatic tissue and the beginning of wash-out time was significantly faster than normal pancreatic tissue. The most common enhancement pattern of malignant diseases was peripheral enhancement with irregular nonenhanced area inside, while the benign diseases appeared homogeneous enhancement. The diagnostic accuracy of CEUS, CECT and biopsy in pancreatic diseases characterization was 87.5%, 81.8% and 92.7%, respectively, which were all significantly different from that of conventional ultrasound (56.9%). But there was no significant difference between CEUS and CECT. Conclusions: CEUS could improve the diagnostic ability in pancreatic diseases characterization. The diagnostic accuracy of CEUS is similar to CECT.