Abstract
Recent testosterone deficiency guidelines from the American Urological Association suggest that total testosterone < 300ng/dL be used as threshold for prescribing testosterone therapy. Treatment for men with total testosterone > 300ng/dL along with symptoms include selective estrogen receptor modulators or human Chorionic Gonadotropin (hCG) as well as a combination of these medications. There exists scant literature regarding the use of hCG monotherapy for the treatment of hypogonadism in men not interested in fertility. To evaluate serum testosterone response and duration of therapy for men treated with hCG monotherapy for symptomatic hypogonadism. We performed a retrospective chart review of men who were receiving hCG. A total of 37 patients met inclusion criteria of being treated with hCG monotherapy (1500 IU SQ weekly) for symptoms of hypogonadism and a total serum testosterone level > 300 ng/dL. We evaluated patient age, treatment indication, hCG dosage, past medical history, physical exam findings and serum testosterone and gonadotropins before and after therapy.
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