2324 A method to estimate the real [Ca 2+] i from signals of fluorescentcalcium dyes

Abstract

1.1. Neuron LP1 of Hermissenda crassicornis shows pronounced anomalous rectification at a membrane potential of −65 mV, or more negative, indicated by a 3- to 4-fold reduction in input resistance, producing an S-shaped current-voltage relationship.2.2. Axotomized LPls show membrane potential bistability since shifts in membrane potential between stable levels at ca −45 and −65 mV accompanied by a change in input resistance occur spontaneously or are induced by current pulses.3.3. Stability at −65 mV appears to be due to activation of the anomalous rectifier.