231 Analysis of corneodesmosomal proteins in nummular eczema skin

Abstract

Nummular eczema, a chronic dermatitis characterized by coin-shaped lesions, was first introduced by Devegie in 1857. In spite of its long history, data regarding its corneodesmosomal components are hardly available in the current literature. We performed this study to investigate whether the distribution of corneodesmosomal components and surface areas of corneocytes in nummular eczema skin lesions are different from those found in healthy skin. Tape-stripping was used to acquire corneocytes from a disease group (n = 24 cases both lesional and non-lesional skin) and a control group (n = 15).