230-POS

Abstract

Objectives The purpose of this study is to describe the racial and socio economic disparities in maternal and fetal deaths related preeclampsia and eclampsia. Methods We obtained weighted estimates of the number of hospitalizations for deliveries complicated by preeclampsia and eclampsia using discharge diagnosis (ICD-9 codes) obtained through the Nationwide Inpatient Sample (NIS) from 2004 to 2011. NIS is a federal database, which contains discharge data from approximately 20% of all annual US hospital admissions and can be weighted to obtain national estimates for all United States hospital admissions. The results are reported as proportion or odd ratios and 95% confidence intervals of maternal and fetal death in preeclamptic and eclamptic deliveries among different races and socio-economic classes. Results Among 33,082,540 deliveries, 708,508 (4.2%) were diagnosed with preeclampsia and eclampsia. There were 2211 maternal deaths and 138,170 of fetal deaths. Preeclampsia and eclampsia were associated with 462 (21.0%) of maternal and 10,372 (7.5%) fetal deaths. Black and Hispanic women were significantly more likely to have maternal deaths and fetal deaths compared to white women. Similarly, women with lower median household income had higher rates of maternal and fetal death compared to women with higher income, (Table 1). These associations were significant after adjusting for other factors. Conclusions This large database analysis showed significant racial and socio economic disparity in maternal and fetal mortality related to preeclampsia and eclampsia in United States. Reasons should be sought to evaluate the causes of such differences and interventions should be directed to these subgroups of women to reduce the rates of maternal and fetal deaths. Disclosures E. Mahmood: None. S. Rana: None. S.S. Shahul: None.