2283 NEAR INFRARED SPECTROSCOPY OF THE DETRUSOR DURING NATURAL BLADDER FILLING

Abstract

You have accessJournal of UrologyUrodynamics/Incontinence/Female Urology: Urodynamics Testing1 Apr 20132283 NEAR INFRARED SPECTROSCOPY OF THE DETRUSOR DURING NATURAL BLADDER FILLING Babak Shadgan, Andrew Macnab, and Lynn Stothers Babak ShadganBabak Shadgan Vancouver, Canada More articles by this author , Andrew MacnabAndrew Macnab Vancouver, Canada More articles by this author , and Lynn StothersLynn Stothers Vancouver, Canada More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.2212AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The blood supply of the detrusor during cyclic filling and emptying is one of the unique physiological features of the bladder as detrusor blood vessels are required to lengthen and shorten, while maintaining sufficient perfusion of the smooth muscle. Understanding the normal pattern of detrusor hemodynamics and oxygenation during periods of filling and emptying helps to identify bladder pathologies that are associated with interruption of the detrusor blood supply that ultimately result in bladder dysfunction. Near infrared spectroscopy (NIRS) is a noninvasive optical technique that uses light to measure changes in tissue chromophor concentrations in real time. The purpose of this study was to investigate the normal pattern of bladder hemodynamics and oxygenation during natural filling using NIRS. METHODS Ten asymptomatic adults were recruited. Patterns of changes in oxygenated (O2Hb), deoxygenated (HHb) and total hemoglobin (tHb) along with detrusor oxygen saturation percentage (TSI%) were studied in all subjects during natural filling using a spatially-resolved NIRS instrument. RESULTS Real time changes in blood volume (tHb) and tissue oxygen saturation (TSI%) in the detrusor were successfully monitored during natural filling. A consistent pattern of gradual increase in detrusor oxygenation and blood volume during bladder filling followed by a drop at the point of urgency were observed in all subjects. Figure 1 shows an example of NIRS data during natural filling. The effects of heart rate and respiratory cycle on detrusor hemodynamics were also identified. CONCLUSIONS Noninvasive NIRS monitors changes in detrusor hemodynamics and oxygenation during bladder filling. Our observation supports the ability of the coiled vasculature in the detrusor to supply a greatly increased surface area of bladder wall during filling. By detecting different patterns of bladder hemodynamics during natural filling, NIRS might provide unique information on quality and type of bladder dysfunctions, noninvasively. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e936-e937 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Babak Shadgan Vancouver, Canada More articles by this author Andrew Macnab Vancouver, Canada More articles by this author Lynn Stothers Vancouver, Canada More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...