Abstract
Background: Neoadjuvant chemotherapy (NCT) is the standard treatment for patients with locally advanced breast cancer (LABC). Circulating endothelial cells (CECs) are cancer biomarkers and crucial for angiogenesis. The relationship between NCT treatment and the number of aneuploid CECs in LABC has not been previously investigated. The aim of this study was to verify this relationship, and to estimate the clinic value of aneuploid CECs in LABC patients with different NCT responses.
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