Abstract
Inflammatory bowel diseases (IBD) are associated with several skin inflammatory diseases but the mechanism responsible for communication between organs is unknown. Local immune activation occurs in part by the action of induced hyaluronidase in the extracellular matrix (ECM) and subsequent recognition of soluble HA fragments. We hypothesized that such HA fragments may also act to enable organ crosstalk between skin and gut. To test this, the intestine was examined in mice expressing hyaluronidase in the skin (K14/Hyal1 mice).
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
