Abstract

Background: Breast cancer patients with skin ulcerations, satellite nodules or peau d’orange at presentation are classified with stage IIIB breast cancer (T4b) as per AJCC 8th edition. Neoadjuvant chemotherapy (NACT), followed by Modified radical mastectomy (MRM), is the commonly accepted treatment in such patients for fear of adverse outcomes with breast conservation surgery (BCS) and uncertainty over sparing initially involved skin irrespective of the response to chemotherapy. Identifying patients with skin resolution post-NACT can help surgeons in decision-making.

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