Abstract

Ecthyma gangrenosum (EG) is an uncommon infectious cutaneous eruption. It typically presents with painless macules, transitions to hemorrhagic vesicles, and eventually evolves into necrotic ulcers. EG should be recognized early and treated aggressively as it is associated with significant morbidity. Because the literature on this disease is limited, we sought to characterize clinical and pathologic features of EG in a large, multi-institution academic center. Patients were identified using the Mass General Brigham Research Patient Data Registry and included individuals with a diagnosis of EG from 1/1980 to 9/2021 seen at Massachusetts General Hospital, Brigham and Women’s Hospital (BWH), and the BWH Faulkner Hospital.

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