Abstract
Rare copy number variants (CNVs) likely play an important role in common childhood neuropsychiatric disorders such as ADHD and OCD. These disorders represent the extremes of broadly distributed behavioral traits that are influenced by underlying variation in fundamental cognitive processes such as response inhibition. Trait-based approaches in a population sample can help reduce heterogeneity and improve the power to detect rare CNVs associated with these disorders. Currently, we do not know the prevalence of CNVs related to neuropsychiatric disorders in youth in the general population.
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