Abstract

Neurologic and myopathic complications are a frequent cause of morbidity in the post transplant (Tx) clinical course. Myopathic discomfort and muscular weakness are known to be related to the use of calcineurininhibitors (CNIs). So far these side effects had to be tolerated due to lack of alternatives to CNIs. The emergence of proliferation signal inhibitors (PSIs) as novel immunosuppressive agents might allow for a change of the maintenance immunosuppressive regimen to avoid disabling CNI-associated myopathy.

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