2185: A comparison study of contrast-enhanced ultrasonography with c-contrast-enhanced computed tomography in enhancement pattern of hepatocellular carcinoma

Abstract

Objectives: To compare contrast-enhanced ultrasound (CEUS) with contrast–enhanced computed tomography (CECT) in enhancement pattern of hepatocellular carcinoma (HCC). Methods: Ninety-two HCC patients with 98 lesions underwent examination of CEUS and CECT. CEUS was performed with SonoVue and contrast pulse sequencing (CPS). CECT was performed with Ultravist and a standard biphasic helical CT scanning procedure. Results: All of the 98 lesions (100%) showed enhancement on CEUS and CECT in arterial phase. The number of the lesions with hyper-enhancing on CEUS and CECT was 98 (100%) and 94 (95.9%), respectively (p = 0.121). Four (4.1%) lesions showed iso-enhancing in arterial phase on CECT. In portal phase, the number of the lesions with hypo-enhancing on CEUS and CECT was 82 (83.7%) and 83(84.7%), respectively (p = 0.845). Peripheral thin-rim-like enhancement was exhibited in 30 lesions (30.6%) on CEUS and 31 (31.6%) on CECT (p = 0.877). With regard to intratumoral vessels, the visualization was found in 94 (95.9%) lesions on CEUS and 36 (36.7%) on CECT (p = 0.000). Conclusions: The enhancement pattern of HCC on CEUS was consistent with that on CECT, whereas CEUS has the advantages of easy performance, real-time scanning and readily available.