2174-PUB: Profiling of Young Diabetes in India: A Cross-Sectional Analysis Report

Abstract

Aim: The purpose of this study was to profile young-onset (defined as up to age 40 years) diabetes patients in India. Methods: The current analysis is a retrospective data analysis of young-onset diabetes patients. Young age diabetes is defined as patients diagnosed with diabetes between 18 to 40 years of age. T1DM and other secondary diabetes were excluded while profiling these patients. Patient’s data was extracted from EMRs of Apollo Sugar Outpatient clinics (n=35) from January 2018 to October 2019. Descriptive statistics were applied to analyze the data and report the results. Results: Of the total 85568 diabetes patient’s records, 4152 (5%) young diabetes patients were identified as fulfilling the criteria of T2DM of early-onset. Males were 2495 (60%) and females were 1657(40%). Mean blood pressure was 122/78 mmHg, average BMI was 28.4 kg/m2, 15% had hypertension, 39% had dyslipidemia and 1% had CAD. Positive family history was recorded in 5% of patients, and 1% were recorded to have current or past smoking. Mean HbA1c was 8.4%, FBG and PPBG were 190 mg/dL and 273mg/dL. Mean cholesterol 179mg/dL, HDL 40mg/dL, LDL 111 mg/dL, and TG 232 mg/dL and creatinine 0.9mg/dL. The average no of antidiabetes drugs prescribed was 2. Nearly 36% of the patients were on oral agents and insulins, 30% were on statins. Conclusions: In our cross-sectional analysis 5% of patients over 18 month’s period had a diagnosis fulfilled the criteria for early-onset diabetes. There was a male preponderance. The average BMI was considerably higher. The majority had poor control and greater than a third of patients were on insulin. Other comorbidities such as hypertension and dyslipidemia were also prevalent. The higher BMI poor control and presence of comorbidities are ominous predicting a higher progression to complications given the longer disease burden in these patients. Our data indicate the need for further efforts in preventing detecting and treating diabetes in this young group of patients. Disclosure N. Nk: None. C. Dwarakanath: None. V. S: None. M. Rm: None. N. Bs: None. S. Das: None. K. Dash: None. S. Paladugu: None. K. Seshadri: None.