Abstract
Objectives: Enteral tube feeding (ETF) has known benefits, improving weight and stabilising lung function in adult patients with CF. The aim of this study was to examine how weight gain is achieved through measurement of fat deposition before and after initiation of ETF. Methods: 6 patients fulfilled the study criteria, having undergone measurement of body composition [DEXA] 1 year prior to staring ETF and up to 18 months post ETF. Percentage change in weight (kg), body fat (%), lean body mass (kg), gynoid fat (%) and android fat (%) were recorded. Results: 6 patients [3M/3F], aged 17.7–33.0 years were eligible to participate. Body mass index at start ETF was 14.7–24.8 kg/m2. Fat deposition in the year after enteral feeding achieved up to 340% increase. Android (central fat) deposition was consistently greater than gynoid fat. 50% of cases had a reduction in lean body mass after start of enteral tube feeding, despite only one case displaying weight loss over this period.
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