Abstract
Failure to respond to anti-Programmed Death receptor-1 (PD-1) treatment has been linked to high levels of transforming growth factor (TGF)-β in the tumor microenvironment (TME). Since TGF-β requires activation to be functional, we evaluated the expression of the receptor glycoprotein-A repetition predominant (GARP), which facilitates TGF-β activation, on oral squamous cell carcinoma (OSCC) surgical resections.
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