2146: The application of tissue-Doppler image-derived Tei index for assessment of regional function

Abstract

Objectives: We investigated whether the tissue Doppler image (TDI)-derived Tei index can reflect left ventricular (LV) regional function. Methods: We prospectively studied 17 patients (mean age 62 ± 9 years, 5 women) with LV regional wall motion abnormalities. The Tei index was measured in basal and mid segments of LV walls from standard apical views (4, 2 and 5-chamber view). We also obtained the peak systolic velocity (Sm), early diastolic velocity (Em), and late diastolic velocity (Am) in each segment. LV wall motion was classified into normal, hypokinesia and akinesia based on visual analysis. Results: The value of TDI-Tei index, Sm, Em and Am were 0.742 ± 0.201, 4.173 ± 1.339, 5.311 ± 1.879 and 5.568 ± 2.360 in akinetic, 0.677 ± 0.101, 4.962 ± 1.565, 5.357 ± 2.072 and 5.219 ± 2.366 in hypokinetic and 0.668 ± 0.135, 5.422 ± 1.526, 6.119 ± 2.372 and 6.806 ± 2.428 in normal segments. The TDI-Tei index in dysfunctional segments (akinesis or hypokinesis, n = 63) were significantly higher than those of normal segments (n = 140), 0.714 ± 0.169 versus 0.668 ± 0.135, p = 0.023, respectively. A significant correlation was also present between TDI-Tei index and Sm (r = -0.302, p < 0.001). Conclusions: We demonstrated that the Tei index can reflect regional dysfunction.