2139 THE ACCURACY OF EVALUATING PROSTATE VOLUME BY THREE IMAGING MODALITIES COMPARED TO REAL PROSTATE VOLUME OF RADICAL PROSTATECTOMY SPECIMENS

Abstract

You have accessJournal of UrologyImaging/Radiology: Uroradiology II1 Apr 20102139 THE ACCURACY OF EVALUATING PROSTATE VOLUME BY THREE IMAGING MODALITIES COMPARED TO REAL PROSTATE VOLUME OF RADICAL PROSTATECTOMY SPECIMENS Adam Zarkadoulias, Eleftherios Chatzidarellis, Andreas Bourdoumis, Nikolaos Antoniou, Charalambos Deliveliotis, and Ioannis Varkarakis Adam ZarkadouliasAdam Zarkadoulias Marousi - Athens, Greece More articles by this author , Eleftherios ChatzidarellisEleftherios Chatzidarellis Chalandri - Athens, Greece More articles by this author , Andreas BourdoumisAndreas Bourdoumis Athens, Greece More articles by this author , Nikolaos AntoniouNikolaos Antoniou Palaio Psychiko - Athens, Greece More articles by this author , Charalambos DeliveliotisCharalambos Deliveliotis Kifisia - Athens, Greece More articles by this author , and Ioannis VarkarakisIoannis Varkarakis Athens, Greece More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2010.02.2240AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To evaluate the accuracy of Transabdominal ultrasound (TAUS), Transrectal ultrasound (TRUS) and Computed Tomography (CT) in the estimation of prostate volume as compared with the volume of the surgical specimen after radical prostatectomy. METHODS Thirty-six patients with localized prostate cancer underwent open radical retropubic prostatectomy during a 9 month period. All patients had prostate volumes evaluated using TAUS and TRUS the day before the operation and CT 1 week earlier. The measurements were performed using the three largest dimensions of the prostate and the classic ellipsoid formula (width x length x height x π/6). The volumes of the specimens were measured after the removal of the seminal vesicles using a volumetric container. Comparisons between the volumes measured with TAUS, TRUS and CT and those of the specimens were performed by paired t-test, with a p value <0,05 considered as statistically significant. Pearson correlation coefficients were calculated between the prostate volumes measured with TAUS, TRUS and CT and the radical prostatectomy specimens. RESULTS The mean prostate volumes with the standard deviation (SD) measured by TAUS, TRUS and CT were 46,1 ± 27,19, 42,5 ± 23,64 and 46,4 ± 23,31 ml respectively, while the mean volume with the SD of the specimens was 44,3 ± 22,22 ml. The differences between the prostate volume measured by TAUS, TRUS and CT and the volume of the radical prostatectomy specimens were not statistically significant (p=0,2, p=0,11 and p=0,13 respectively). The prostate volumes measured with TAUS, TRUS and CT correlated significantly with the prostate volumes obtained from radical prostatectomy specimens (r=0,89, r=0,94, r=0,91, respectively). Overall TAUS and CT slightly overestimated the prostate volume as compared with the specimen volume due to difficulties in defining the prostatic apex, while TRUS underestimated it due to problematic median prostatic lobe imaging. CONCLUSIONS No statistically significant differences were found between the TAUS, TRUS and CT based prostate volume measurement as compared with the volume of the radical prostatectomy specimen. All three modalities are equally accurate for prostate volume evaluation and can be used for clinical decision making. © 2010 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 183Issue 4SApril 2010Page: e831-e832 Peer Review Report Advertisement Copyright & Permissions© 2010 by American Urological Association Education and Research, Inc.MetricsAuthor Information Adam Zarkadoulias Marousi - Athens, Greece More articles by this author Eleftherios Chatzidarellis Chalandri - Athens, Greece More articles by this author Andreas Bourdoumis Athens, Greece More articles by this author Nikolaos Antoniou Palaio Psychiko - Athens, Greece More articles by this author Charalambos Deliveliotis Kifisia - Athens, Greece More articles by this author Ioannis Varkarakis Athens, Greece More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...