212 Tumor adjacent cytokine factories for eradication of ovarian cancer tumor burden in mice through cytotoxic T-cell activation with safe and predictable dosing in non-human primates

Abstract

BackgroundPro-inflammatory cytokines have been approved by the FDA for the treatment of metastatic melanoma and renal carcinoma.1 2 However, effective cytokine therapy is limited by its short half-life in circulation...