Abstract
Abstract21T MR microimaging with the first use of troponin nanoparticles enhances the visualization of cardiac muscle fibers and offers technical advancement for the future. Diffusion weighting offers fiber tracking and functional analysis. Image processing offers heart probabilistic atlas and maps.http://www.ismrm.org/10/program/ELECTRONICPOSTERS.htm
Highlights
The route and location of nanoparticles were visible on images
The microimaging technique by 21T MRI is technical advancement suitable to design functional imaging contrast agents
Summary
A nanoparticle (SPIOT) containing antitroponin coated and polyethylene encapsulated biotin-avidin-iron-oxide core in center was prepared. Microimaging of rat heart at 21 Tesla MR by rapid 3D fast low angle shot, 3D gradient echo flow compensated and mutislice multiecho MR imaging techniques. Image processing of the rat heart images for the measurement of cardiac wall, ventricle volume, aorta, possible orientation details of cardiac myofibrils tissue. Cardiac atlas with cardiac shape, texture and motion analysis
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