Abstract
Chronic perineal neuropathic pain can be quite challenging to manage, primarily due to overlapping clinical presentation of multiple clinical entities, such as inferior pudendal neuritis, pudendal neuritis, pyriformis syndrome, and obturator neuritis. A thorough history, examination, and series of diagnostic blocks may be required to accurately diagnose the site of pain in patients suffering from chronic perineal, buttock, and/or pelvic pain. Chronic perineal pain secondary to inferior cluneal nerve involvement can often be misdiagnosed or remain undiagnosed, leading to significant morbidity affecting quality of life. Intractable perineal pain secondary to inferior cluneal neuritis can respond to advanced neuromodulation options such as peripheral nerve stimulation.
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