Abstract
mented significant associations of MPV with type 2 diabetes mellitus, pre-diabetes, obesity, and other metabolic risk factors. The objectives of this study were to examine relationship between MPV and varicocele to clarify the etiopathogenesis of varicocele. METHODS: MPV levels were measured in 60 varicocele subjects (group I) and 57 healthy controls (group II) from 2009 to 2010. Age was were similar between two groups. The diagnosis of varicocele was based on the findings from both physical examination and color Doppler ultrasound. RESULTS: The average patient age at the time of examination was 28.12 6.4 years in group I and 28.10 5.8 in group II. Mean MPV levels were 9.59 1.58 fl in group I and 7.97 0.88 fl in group II. MPV levels were statistically significantly higer in group I than in group II (p 0.001). Positive correlations were found between the MPV and varicocele grade like as between MPV and diameter of left spermatic vein (p 0.05). CONCLUSIONS: The increase in MPV is independent of the disease, and the increase in varicocele grade is associated with higher MPV in varicocele patients. Based on the importance of the vascular component in the pathophysiology of varicoceles, we would suggest to do more studies with platelets in varicocele patients.
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