2091088 Detection And Characterization of Focal Lesions Of The Prostate Using Shear Wave Elastography (SWE)

Abstract

ObjectivesThe purpose of this study is the access to the role of Shear Wave Elastography (SWE) in the detection and characterization of focal lesions of the prostate.MethodsWe prospectively examined 150 consecutive patients in a 6-month period with TRUS, SWE and TRUS-guided biopsies. The median patient age was 59 years (range 45-88 years), the median serum PSA level was 8.5 ng/ml (range 1,9-47 ng/ml) and the median prostate volume was 55 ml (range 25-180 ml). All examinations were performed on an Aixplorer/Supersonic system with an end-fire transrectal probe (SE 12-3). Additionally, in cases where no TRUS or SWE visible lesions were present, 20 systematic biopsies were performed in all prostate segments.ResultsProstate cancer (PRCA) was found in 60/140 patients (43%). A total number of 69 PRCAs were proved by TRUS-guided biopsies. The SWE findings were positive in 50 (73%) of PRCAs. In particular, 12 (17.4%) PRCAs were positive only on SWE, including 6 in the peripheral zone (PZ) and 7 in the transitional zone (TZ) lesions. The SWE findings were negative in 17 (25%) lesions, all in the PZ. SWE findings in these cases showed disagreement with tumor location or undetectable lesion. 15 of these lesions were judged as positive on TRUS.ConclusionsSWE in conjunction with TRUS shows promising results in the detection of PRCA. Meticulous technique and strict protocol are necessary. SWE helps guiding needle biopsy and proving PRCA in atypical lesions in the PZ and the TZ. ObjectivesThe purpose of this study is the access to the role of Shear Wave Elastography (SWE) in the detection and characterization of focal lesions of the prostate. The purpose of this study is the access to the role of Shear Wave Elastography (SWE) in the detection and characterization of focal lesions of the prostate. MethodsWe prospectively examined 150 consecutive patients in a 6-month period with TRUS, SWE and TRUS-guided biopsies. The median patient age was 59 years (range 45-88 years), the median serum PSA level was 8.5 ng/ml (range 1,9-47 ng/ml) and the median prostate volume was 55 ml (range 25-180 ml). All examinations were performed on an Aixplorer/Supersonic system with an end-fire transrectal probe (SE 12-3). Additionally, in cases where no TRUS or SWE visible lesions were present, 20 systematic biopsies were performed in all prostate segments. We prospectively examined 150 consecutive patients in a 6-month period with TRUS, SWE and TRUS-guided biopsies. The median patient age was 59 years (range 45-88 years), the median serum PSA level was 8.5 ng/ml (range 1,9-47 ng/ml) and the median prostate volume was 55 ml (range 25-180 ml). All examinations were performed on an Aixplorer/Supersonic system with an end-fire transrectal probe (SE 12-3). Additionally, in cases where no TRUS or SWE visible lesions were present, 20 systematic biopsies were performed in all prostate segments. ResultsProstate cancer (PRCA) was found in 60/140 patients (43%). A total number of 69 PRCAs were proved by TRUS-guided biopsies. The SWE findings were positive in 50 (73%) of PRCAs. In particular, 12 (17.4%) PRCAs were positive only on SWE, including 6 in the peripheral zone (PZ) and 7 in the transitional zone (TZ) lesions. The SWE findings were negative in 17 (25%) lesions, all in the PZ. SWE findings in these cases showed disagreement with tumor location or undetectable lesion. 15 of these lesions were judged as positive on TRUS. Prostate cancer (PRCA) was found in 60/140 patients (43%). A total number of 69 PRCAs were proved by TRUS-guided biopsies. The SWE findings were positive in 50 (73%) of PRCAs. In particular, 12 (17.4%) PRCAs were positive only on SWE, including 6 in the peripheral zone (PZ) and 7 in the transitional zone (TZ) lesions. The SWE findings were negative in 17 (25%) lesions, all in the PZ. SWE findings in these cases showed disagreement with tumor location or undetectable lesion. 15 of these lesions were judged as positive on TRUS. ConclusionsSWE in conjunction with TRUS shows promising results in the detection of PRCA. Meticulous technique and strict protocol are necessary. SWE helps guiding needle biopsy and proving PRCA in atypical lesions in the PZ and the TZ. SWE in conjunction with TRUS shows promising results in the detection of PRCA. Meticulous technique and strict protocol are necessary. SWE helps guiding needle biopsy and proving PRCA in atypical lesions in the PZ and the TZ.