2084581 Acoustic Radiation Force Impulse Imaging of Thyroid Nodules at Medic Medical Center, Viet Nam

Abstract

The aim of the present study was to evaluate the VTQ of normal thyroid tissues, benign and malignant thyroid nodules. Besides, VTI (Virtual Touch Tissue Imaging) of ARFI-Imaging was assessed in these objects as well. One hundred and thirty nodules underwent conventional ultrasound, including Color Doppler ultrasound using a 7.5MHz linear transducer. Next, nodule stiffness were measured and assessed by VTQ and VTI of ARFI-Imaging (Acuson Siemens S2000). FNAC (Fine needle aspiration cytology) under ultrasound guide was used as reference method for the diagnosis of benign and malignant thyroid nodules. 103 benign and 27 malignant thyroid nodules. The median velocity of ARFI-imaging in the normal tissue as well as in benign and malignant nodules was 1.51m/s (range 0.84-3.00m/s), 2.15m/s (range 0.8-4.04m/s), 3.21m/s (range 0.9-9.22m/s), respectively. At the cut-off of 2.16m/s, the sensibility and specificity in differentiation of benign and malignant thyroid nodules were 79.4% and 53.7% (AUROC =0.731, p<0.0001). Chi-square statistic showed there was a relationship between VTI and the differentiation of benign and malignant thyroid nodules. ARFI can be performed in thyroid nodule with reliable results. The combination of VTQ and VTI can give a better differential diagnosis. Larger studies are awaited.