208-POS

Abstract

Objectives To assess the Microlife 3AS1-2, a semi-automated oscillometric BP device, compared to mercury sphygmomanometry for use in pregnancy and pre-eclampsia in a low resource setting, according to the requirements of the British Hypertension Society (BHS) Protocol and the International Organization of Standardization (ISO). Methods Prospective observational study, using validation methods recommended by the BHS. 45 pregnant women were recruited from Kimberley Hospital, South Africa, of which 15 were pre-eclamptic. 10 women were in their second trimester, 10 were in their third trimester and 10 had an arm circumference >35 cm. All participants provided written consent. Any subject with cardiac arrhythmia or unclear Korotkoff sounds was excluded. Results The Microlife 3AS1-2 device achieved an overall B/A grade in pregnancy (including pre-eclampsia) and passed all the BHS protocol requirements. The device achieved the ISO standard for mean difference and standard deviation (⩽5 ± 8 mmHg) in pregnancy (including pre-eclampsia). Conclusions The Microlife 3AS1-2 device can be recommended for use in pregnancy, including pre-eclampsia, according to BHS and ISO protocols. As well as demonstrating accuracy in a pregnant low-resource population, it also fulfils all of the requirements stipulated by the World Health Organization for an automated device suitable for use in a low-resource setting. This makes it the ideal device for use in antenatal clinics and primary health-care facilities in low- and middle-income countries. Table 1. Results according to the BHS protocol. Grade ⩽5 mmHg ⩽10 mmHg ⩽15 mmHg Mean difference ± SD (mmHg) Pregnancy (n = 30) Systolic BP A 63 86 96 −2.9 ± 7.4 Diastolic BP A 81 93 99 0.3 ± 5.0 Pregnancy (incl. pre-eclampsia (n = 45)) Systolic BP B 58 82 95 −3.8 ± 7.3 Diastolic BP A 70 90 97 −1.5 ± 6.2 Disclosures H.L. Nathan: None. A. de Greeff: None. N.L. Hezelgrave: None. K.E. Duhig: None. L.C. Chappell: None. A.H. Shennan: None.