Abstract
When bringing regenerated cartilage into practical use, due to its piece-to-piece property difference, non-invasive evaluation should be developed before implantation. We intended to achieve non-invasive assessment of articular cartilage by applying terahertz technology. The purpose of this research is to clarify the relation between terahertz spectra and cartilage characteristics such as mechanical strength, extracellular matrix structure. In this paper, by applying dielectric analysis to transmission spectra of terahertz wave, we clarified slow relaxation strength of water molecular, which can be corresponding to the amount of free water in cartilage. The amount of free/bound water in cartilage is one of the factors that decide the mechanical properties of cartilage. To verify cartilage characteristics, we performed mechanical test and determined the amount of extracellular matrix. A comparison between slow relaxation strength and cartilage characteristics shows that terahertz technology can be one way of measuring water status and its characteristics.
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