2034 QUANTATIVE SHEAR WAVE ELASTOSONOGRPAHY IN THE DETECTION OF PROSTATE CANCERS

Abstract

You have accessJournal of UrologyImaging/Radiology: Uroradiology I1 Apr 20122034 QUANTATIVE SHEAR WAVE ELASTOSONOGRPAHY IN THE DETECTION OF PROSTATE CANCERS Sarfraz Ahmed, Omar Aboumarzouk, Stephen Lang, and Ghulam Nabi Sarfraz AhmedSarfraz Ahmed Dundee, United Kingdom More articles by this author , Omar AboumarzoukOmar Aboumarzouk Dundee, United Kingdom More articles by this author , Stephen LangStephen Lang Dundee, United Kingdom More articles by this author , and Ghulam NabiGhulam Nabi Dundee, United Kingdom More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.2198AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Shear wave elastosonography is a new method of obtaining quantitative tissue elasticity data during transrectal ultrasound biopsies procedure. The aims of this study were (1) to determine the whether shear wave elastsonography can help in picking up extra cancer foci to the currect12 core biopsies technique (2) to compare quantitative shear wave elastosonography for benign/malignant classification. METHODS Using the Aixplorer® ultrasound system (SuperSonic Imagine, Aix en Provence, France), 32 men with suspected prostate cancer underwent transrectal 12- core systematic biopsies. Additional biopsies were directed using shearaave mode of the machine, if the lesions appeared to be outside the biopsied area. Two orthogonal elastography images were obtained of each region of the biopsied areas. Elastsonography measurements were correlated with histology results. After preliminary experience with 10 patients a mean elasticity cut off value of 70 kilopascals (kPa) was selected for benign/malignant differentiation. RESULTS Thirty one of 32 men had abnormal foci seen on transrectal elastosonography. Twenty one of these lesions were diagnosed as cancer or PIN. There were fourteen foci which were not targeted by 12-core-systematic biopsies and could have been missed, had shearwave elastosonography not being used in these men. All of these cancers were significant with majority being in the lateral zone. One man missed on two previous 12-core biopsies sets was diagnosed with shear wave directed biopsies on the third occasion. There was a significant difference between elasticity measurement of benign and malignant tissues ( p value 0.028). CONCLUSIONS Shear wave elastography provides quantitative information about the prostatic tissue and in our preliminary observation can accurately direct biopsies to the cancer foci within the prostate. This has huge potential for focal treatment and future prostate biopsies protocols. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e820-e821 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information Sarfraz Ahmed Dundee, United Kingdom More articles by this author Omar Aboumarzouk Dundee, United Kingdom More articles by this author Stephen Lang Dundee, United Kingdom More articles by this author Ghulam Nabi Dundee, United Kingdom More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...